ASSOCIATION OF IMMUNE RESPONSE WITH EFFICACY AND SAFETY OUTCOMES IN ADULTS WITH PHENYLKETONURIA ADMINISTERED PEGVALIASE IN PHASE 3 CLINICAL TRIALSRESEARCH IN CONTEXT

Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety and efficacy.Methods: Immunogenicity was assessed during induction, upward titration, and mainten

Architecture is considered as a language during the last four decades, contemporary studies had presented this trend through different cognitive approaches which includes both the fields of meaning and semiotic as semantic expressions in all events.In Arab countries, it has emerged in reactions concentrating on imitating the global experiences thus

With the globalization of trade, people have become enlightened and demanding consumers as regards the origin of their food and the environment dea eyewear in which it is produced.The concept of geotraceability described in this article responds to that requirement by combining geographical information with conventional traceability data.The inclus

With the mercury metallic lexus ever-increasing use of nanoparticles in immunosensors, a fundamental study on the effect of epitope density is presented herein, with a small molecule epitope, on the performance of the displacement assay format in an enzyme-linked immunosorbent assay (ELISA).Thiolated bisphenol A (BPA) functionalized gold nanopartic

A typical muscle variation of latissimus dorsi - the axillary arch is represented by the muscular or fibromuscular slip detached from the anteroinferior border of the musculus latissimus dorsi passing over the axilla under the axillary fascia crossing the medial side of the brachial plexus to continue as a septum intermusculare mediale brachii dist